Ampicillin is an antibacterial drug, approved for the treatment of infectious diseases in adults and children. This antibiotic easily penetrates into all organs, tissues and body fluids.
The International Pharmaceutical market offers injectable and oral forms of Ampicillin.
For oral therapy of infectious diseases, patients may be prescribed Ampicillin capsules or suspension. Doctor can recommend to buy:
For the convenience of dosing Ampicillin suspension, each pack includes a measuring spoon or a syringe dispenser.
For injection therapy of bacterial infections, patients can be prescribed intravenous or intramuscular injections of Ampicillin:
- 125 mg
- 250 mg
- 500 mg
- 1 gram
- 2 grams
Ampicillin is sensitive to the action of bacterial enzymes (lactamases) that are produced by microorganisms in response to the antibiotic action.
These enzymes can destroy the antibiotic. Therefore, to improve the efficiency of therapy, Ampicillin started to be used in combination with beta-lactamase inhibitors (incl. Sulbactam).
The US market offers several combined medications that contain Ampicillin and Sulbactam. These antibiotics are only available in injectable form and one of the best known medications is Unasyn.
Ampicillin in the international market
Despite the emergence of new antimicrobial agents, Ampicillin remains the drug of choice for the treatment of sepsis in neonates and children, enterococcal infections and bacterial meningitis.
Since Ampicillin was discovered, a large number of drugs appeared on the international market on the basis of the antibacterial agent.
US distributors of the antibiotic Ampicillin are companies Parke Davis, West-Ward, Hanford, Sandoz, Mustafa Nevzat, Aurobindo, Sagent, Hospira, ACS Dobfar, Mylan.
Ampicillin is supplied to the international pharmaceutical market under various original names, including:
Indications for use
Ampicillin is used for the treatment of bacterial infections in children and adults. Antibiotic is effective in the treatment of the following diseases:
Respiratory tract infections
- lung abscess
Urinary tract infections
Ear, nose and throat infections
Gastrointestinal tract infections
- enteric fever
Ampicillin may also be used to treat bacterial meningitis and endocarditis, gonorrhea and gynecological infections. The antibiotic is effective in the treatment of skin and skin structure infections in children and adults.
Method of administration and dosage regimens
When buying Ampicillin, you need to pay attention to the amount of the active ingredient and dosage form.
It is recommended to take Ampicillin capsules and suspension orally, half an hour before a meal or 2 hours after a meal. Capsules should be swallowed whole, without opening their contents and without chewing.
The dose and duration of treatment for a bacterial infection is determined with the account taken of:
- the patient’s age
- severity of the disease
- localization of infection
- sensitivity of the pathogen
Ampicillin doses for children are calculated based on the child’s body weight. The lowest effective dose of Ampicillin should be used in neonates and young infants. Due to the fact that the urinary system in infants is not yet fully formed, the antibiotic should be used with caution in this group of patients.
- Depending on the severity of the infection, the therapeutic dose for neonates may be 50 to 200 mg of Ampicillin per kg of body mass per day.
- Children aged 12 months and older are usually prescribed 200mg of Ampicillin per kg of body weight per day. The daily dose is divided into four doses.
- Children weighing 40 kg or more are prescribed adult doses of Ampicillin.
- When non-standard doses should be used for children, better buy Ampicillin solution.
Treatment of infections in adults, elderly and pediatric patients
Older patients with a normal renal function are prescribed the usual adult doses. Older patients with renal impairment may require adjustment of the antibiotic dose.
Side effects and contraindications
Before you buy Ampicillin online, you can get reliable information about the side effects and contraindications to the use from the pharmacist of the online pharmacy. As a rule, patients tolerate Ampicillin well. Most prone to the development of undesirable effects are individuals with a history of urticaria, hay fever or allergy.
During the use of the antibiotic, patients often observe reactions from the gastrointestinal tract, like diarrhea, nausea and vomiting. Sometimes, Ampicillin can cause pseudomembranous colitis. These undesirable effects develop most often in oral antibiotics administration.
Ampicillin injection can provoke skin rash, dermatitis, and erythema. At the first signs of skin disorders, patient should stop taking the drug and consult a doctor.
Just like other antibiotics, Ampicillin can interact with other drugs. The following drugs can affect the therapeutic effectiveness of the antibiotic:
Ampicillin can reduce the effectiveness of estrogen-containing oral contraceptives. Therefore, women who take this antibiotic should use additional contraception methods.
Combined use of Ampicillin with anticoagulants (Phenindione, Warfarin) enhances the anticoagulant effect and may change the INR indicators that are used to measure the time it takes your blood to clot.
Range of antimicrobial activity
If you buy Ampicillin, you will get a broad-spectrum antibiotic. Ampicillin is active against the majority of aerobic Gram-positive and Gram-negative bacteria.
* not producing penicillinase
Ampicillin has no effect on staphylococci that produce the enzyme penicillinase.