Doxycycline is an antibiotic from the class of tetracyclines. It is used to treat a wide variety of bacterial infections and is most effective in the treatment of some of them, for example, rickettsial diseases.
Specific examples of diseases, for the treatment of which people use Doxycycline:
- Inclusion conjunctivitis
- Intestinal amebiasis
- Tick fevers
- Lymphogranuloma venereum
- Nongonococcal urethritis
- Rocky mountain spotted fever
- Typhus fever
- Uncomplicated gonorrhea
- Wound infections
Doxycycline does not guarantee protection from malaria, yet it can be used as an anti-malarial agent for the prevention of this disease.
Doxycycline can be delivered into the body or to the site of infection in various ways. Different methods of administration allow achieving the necessary concentration of antibiotic where it is needed the most.
Typically, Doxycycline is used orally, absorbed through the digestive tract and enters the bloodstream. Parenteral forms of this antibiotic enter the infection site bypassing the gastro-intestinal tract.
Several dosage forms of Doxycycline are available at the international pharmaceutical market. You can buy Doxycycline as:
- Oral suspension
- Solution for injection
Tablets, capsules and periodontal gel can be of immediate or sustained release. Different dosage forms contain Doxycycline as monohydrate, calcium or hyclate. Indications may vary, depending on the administration mode of the antibiotic.
Doxycycline is produced by dozens of pharmaceutical companies in all regions of the world. The list of the most popular and commonly used Doxycycline-containing medications includes brand antibiotics:
- Doxy 100
- Vibra -Tabs
Range of antimicrobial activity
Doxycycline is a prescription antibacterial agent with a broad spectrum of action. It can be prescribed by the physician based on the type of infection and suspected bacteria.
Doxycycline inhibits the vital functions of a wide spectrum of bacteria and some parasites. This drug of the tetracycline class is active against:
- Escherichia coli
If you bought Doxycycline pills or solution and began the antibacterial therapy, observe the recommendations for use. Failure to comply with the dosing may slow down the treatment of the bacterial infection. Doxycycline is not effective against viruses, and should never be used when a virus is suspected or diagnosed.
Mechanism of action
During clinical trials, Doxycycline showed a high microbial cure rate and activity against a variety of pathogens. Therefore, this antibiotic is used to treat many infections.
Recommended dosing schedule
To be effective, Doxycycline should be used on a regular basis, once or several times a day. If you do not know how often you should take the antibiotic, ask your doctor or pharmacist for help, or read the leaflet. Follow all instructions carefully.
If the decision is made to initiate an infection treatment with oral doses of Doxycycline, the following guidelines should be followed generally:
Single oral doses of Doxycycline vary from 20 mg to 200 mg. On the first day of treatment, higher doses may be administered, than on the following days.
Typically, the duration of Doxycycline use in oral doses is up to 1-2 weeks. If you are about to run out of the medication, buy Doxycycline in advance to not miss the regular doses.
Treatment of certain diseases can be long-lasting, for example:
Doxycycline gel is used only for the treatment of periodontitis. It is introduced directly into the infected pockets around the teeth. The dentist will determine the dose and duration of treatment.
Solution for injection Doxycycline is commonly used in hospitals, when oral therapy is not indicated. The doctor will determine the dose, frequency of the antibiotic administration and the treatment duration.
Never use high doses of Doxycycline to make up for the dose that you missed or forgot to take. To reduce the risks of drug interactions and side effects, tell your doctor about any medications that you use.
Side effects and cautions
Like any other drug used for the infection treatment, Doxycycline may cause adverse reactions. Some of them, such as allergies, can be severe, yet most are minor and temporary.
- Decreased appetite
- Change in tooth color
This is not a complete list of reactions to Doxycycline. If these occur, the benefit of continuing treatment should be higher than potential risks.
If you bought Doxycycline for yourself, never give it to children, if the antibiotic is not prescribed by a doctor. When children use Doxycycline, especially for a long time, the risk of permanent teeth discoloration increases. This side effect occurs in patients who use any antibiotic from the tetracycline class.
Patients with a liver disease should use Doxycycline with caution. If your skin becomes more sensitive to sunlight during the antibacterial treatment, protect it when you are in the sun.
Tell your doctor if you are abusing alcohol or using drugs from the following list:
These drugs and substances may interact with Doxycycline, though not in every case.
If you took a very high dose of Doxycycline, immediately report it to your doctor. Gastric lavage can help reduce diarrhea, vomiting, nausea, or other symptoms of an overdose. Dialysis is not effective in reducing the symptoms of an overdose with Doxycycline.