Keflex is an antibiotic of cephalosporins group, widely used to treat infectious diseases in children and adults. The popularity of the antibiotic is due primarily to good tolerability and low toxicity.
Keflex is supplied on the international market in the form of oral suspensions, capsules and tablets with various doses of Cephalexin. In local and online pharmacies, you can buy :
Keflex Suspension is intended for use in children and patients with impaired swallowing function.
The antibiotic is supplied in 100 ml and 200 ml bottles as a white powder, which becomes red after reconstitution.
Keflex antibiotic was developed over 40 years ago by Eli Lilly Company. Despite the fact that many Keflex generics are available for sale in pharmacies these days, the proprietary drug by Eli Lilly remains one of the most popular antibiotics in the US and other countries of the world.
Top brand Keflex generics in the international market
Indications for use
Due to its good tolerability and a favorable safety profile, the antibiotic Keflex (and its generics) can be used to treat infectious diseases in adults and children (starting from the 13th month of life). The antibiotic possesses a broad spectrum of action and is used to treat the following infections*:
Respiratory tract infections
Genitourinary tract infections
Skin and skin structure infections
* Depending on the country where Keflex is approved, indications for the antibiotic use may differ. Patients who bought Keflex in the UK, may find treatment of dental infections in the list of indications.
Method of administration and dosing regimen
The oral suspension is prepared immediately before the first application. The ready-to-use suspension should be stored in a fridge or a cool place at a temperature of 2°C to 15°C. The antibiotic is suitable for use for 10 days.
The dosing regimen of Keflex is selected taking into account the patient’s age and the disease severity. The treatment course for uncomplicated infections is 7 days. Treatment of severe infections may require the use of an antibiotic for 14 days.
Recommended dosing scheme for adults, elderly patients and teenagers over 15 years of age
Mild and moderate infections
- 250 mg Keflex every 6 hours
- 500 mg Keflex every 12 hours
- 1 g to 4 g Keflex per day
- The daily dose is divided into two or four doses
Pediatric doses of Keflex are calculated with the account taken of the child’s body weight and response to the antibiotic therapy performed.
Recommended dosing scheme for children (over 1 year of age)
Mild and moderate infections
- dose varies from 25 mg to 50 mg Keflex per kg body weight per day
- the daily dose is divided into 4 parts, which are taken at regular intervals
- 50 mg to 100 mg of Keflex per kg of body weight per day, divided into four doses
- 75 mg to 100 mg of Keflex per kg of body weight per day, divided into four doses
To treat infections in patients with a mild renal insufficiency, Keflex is used in conventional doses. The antibiotic may accumulate in patients with a chronic kidney disease, so patients with severe kidney disorders require a lowering of the therapeutic doses of the drug.
If you buy Keflex, you get an antibiotic with a good tolerability and low risks of side effects. Despite good tolerability, Keflex may cause discomfort and undesirable effects in some patients. Most of them are transient and do not require the antibiotic abolition.
During the course of Keflex, the most frequently reported side effects are diarrhea, nausea, stomach pains, headache, and loss of appetite. Colitis and such skin disorders, like red wheals on the skin, blistering and itching may develop in a small number of patients.
Highly rare, Keflex can cause difficulty in breathing, swelling of the face, eyelids or lips. If any of these severe reactions manifest, stop taking the antibiotic and consult a doctor.
Drug Interactions and contraindications
Keflex rarely interacts with other medications. However, there are some drugs, which are not recommended for combining with the antibiotic. These include:
Keflex should be combined with caution with cytotoxic drugs that are used to treat leukaemia. Combination of drugs can provoke a potassium deficit in the body, which leads to violations of the functions of many organs.
Keflex is contraindicated in patients with hypersensitivity to any component of the antibiotic, as well as patients who experienced a major allergy to penicillin.
During pregnancy, Keflex should also be used with caution. Despite the lack of data indicating a violation of normal fetal development, pregnant women should use an antibiotic only if the intended benefit to the mother exceeds the potential risk to the fetus.