Antibiotics: Right Choice for Fighting Bacterial Infeсtions Successfully

Macrobid Online

Mechanism of action
Urinary traction infections
Side effects
Macrobid price online (without prescription)
Macrobid price online (with prescription)
List of Macrobid Generic Brands
Leaflet and booklet downloads
Clinical References and resources

Macrobid is oral urinary tract anti-infective agent. It has a broad spectrum of antimicrobial activity, is not considered to be carcinogenic and is therefore often used in urological clinical practice.

Macrobid is used for the prevention and treatment of acute or recurrent bacterial infections that occur in different parts of the urinary tract, including:

  • Bladder
  • Kidneys

Macrobid is produced in the form of hard gelatin capsules. Brand name “Macrobid” is imprinted on one side of the capsule. Each Macrobid capsule contains 100mg of the active substance Nitrofurantoin in two forms:

  • as macrocrystals 25 mg.
  • as monohydrate 75 mg.

Due to this combination, the active substance Nitrofurantoin dissolves and is absorbed in the gastrointestinal tract in a gradual manner. As a result, a Nitrofurantoin concentration is maintained stable in the patient’s urine, and  the desired antibacterial effect is provided.

If you are looking for a reliable and safe bactericide, buy Macrobid. This antibiotic affects the vital biochemical processes of pathogenic bacteria and causes their death.


Macrobid has a complex and unique mechanism of action. The therapeutic effect is achieved through the inhibition of the synthesis and/or slow down of the bacterial:

  • DNA
  • RNA
  • Protein
  • Metabolism
  • Cell wall

Other Nitrofurantoin-containing antibiotics have similar mechanisms of action. They are sold under such brand names, as:

  • Furadantin
  • Aratoin
  • Macrodantin
  • Genfura
  • Nifuran
  • Urantoin

It should be noted that these medications contain Nitrofurantoin in a single form. Their dosing frequency differs from that of Macrobid, although indications are the same – i.e. treatment of urinary tract infections.

You can buy Macrobid generics called Nitrofurantoin (Monohydrate/Macrocrystals). They should be taken as often as Macrobid capsules should, yet may be available at a lower price than the branded antibiotic.

If you do not know how to use Macrobid, consult an urologist or pharmacist. They will give precise instructions on how many capsules should be taken and how long the treatment should last.

If you decide to begin using Macrobid to treat urinary traction infections, you need to comply with the following recommendations:

Take Macrobid orally together with food or milk.

Take 1 capsule of Macrobid 100mg every 12 hours, in the morning and in the evening.

Duration of therapy may vary, but typically it is:

  • 7 days – UTI treatment
  • 4 days – UTI prevention

100mg Macrobid capsules are generally not indicated for children younger than 12 years of age. Other antibiotics that contain small amounts of Nitrofurantoin are used to treat urinary tract infections in children.

Macrobid is contraindicated in patients:

  • At the age of up to 4 weeks.
  • In the middle and end of the 3 pregnancy trimester.
  • Immediately before or during labor.
  • With certain kidney diseases.
  • With allergy to the active substance.

Macrobid is clinically proven to be effective for the treatment of infections in different parts of the urinary system. However, along with a useful antibacterial effect, the drug may cause adverse reactions, as well. If you decide to buy Macrobid, you can check with your pharmacist for frequent and rare side effects.

Most common side effects during Macrobid use are:

  • Flatulence
  • Headache
  • Nausea

Rarer body’s response to the antibiotic are loss of appetite, dizziness, shortness of breath, cough, drowsiness, abdominal pain, chest pain, diarrhea, swelling and hives.

Macrobid is highly soluble in water. Therefore, during the period of the antibiotic use, urine may change color and become brown. This is quite normal and is not a reason to stop the pharmacotherapy for upper and lower urinary tract infections.

Consult an urologist or other physician as soon as possible, if you encounter any problems when using Macrobid, even if you do not think that they are associated with the antibiotic or are not listed in the leaflet or into this review.

Macrobid may interact with certain medications, including:


Uricosuric agents

Quinolone anti-infectives

Oral contraceptives

Consult an urologist if you are using or are about to use any medications, including those that are available without a prescription. If you bought Macrobid in an online pharmacy, you can get a free consultation.

Do not stop taking your daily Macrobid dose of 200mg until you finish the entire course, prescribed by the urologist. Pathogenic bacteria that were not destroyed can start reproducing again, and the disease can return.

Macrobid is not effective against urinary tract infections caused by viruses.

Antibiotic is active against bacteria, including the following:

  • Citrobacter
  • Enterobacter
  • Klebsiella
  • Escherichia
  • Staphylococcus
  • Enterococcus

Macrobid destroys a wide range of bacteria that cause infections of the urinary system, though not every strain is susceptible to the antibiotic. Urinary tract infections are unpleasant, yet they can be easily cured with Macrobid 100mg capsules.

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